For quantitative in vitro determination of Microalbumin by immunoturbidimetry in urine. State Liquid Storage temp. 2 / 8 ºC Technique Immunoturbidimetric method PRINCIPLE The reagent is a solution of goat anti-human albumin, which reacts with the albumin present in the urine, producing antigen-antibody aggregates. The formation of these aggregates produces a change in the Abs. system directly proportional to the protein concentration of the sample. By means of a calibration curve, where absorbance is related to the albumin concentration, it is possible to quantify the sample concentration. DIAGNOSTIC USE Microalbuminuria is the term used to describe an increase in urinary excretion of albumin above the reference interval for healthy non diabetic patients (0-20 mg/L). It is considered microalbuminuria when the urinary albumin concentration falls between 20 and 200 mg/L. The increase in urinary albumin loss is considered a clinical indicator of a failure of the renal function in diabetic patients. A single test result can not be used to make a clinical diagnosis. It should integrate clinical and laboratory data.
